More than two million people have now received their first dose of a Covid vaccine, according to figures from Public Health Wales.
2,019,160 people have now received their first dose— equivalent to 64% of the population.
915,674 people have also received their second vaccination— or 29% of the population.
The announcement comes as the country transitions to alert level two and as indoor hospitality reopens on Monday (17 May).
International travel will also resume on Monday (17 May), although the Welsh Government is advising people to only travel abroad for essential purposes.
Health Minister Eluned Morgan described reaching the milestone as a "fantastic achievement."